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Description: Peptides are novel suit of biopharmaceuticals. Bioactive peptides may exhibit molecular targets for development of drugs. Peptide derived from plants and animal products such as milk has the potential to behave as an anticancer agent. Camelina is an oil seed crop and is grown only on a small scale in Canada and is gaining importance as an attractive alternative crop. This project concerns identification and development of peptides such as cecropin from Camelina. Cell viability evaluated by MTS cell proliferation assay in the carcinoma cells provides sensitivity to the camelina peptide treatments. The immunocytochemical analysis and confocal laser scanning microscopy reveals mechanisms of action of camelina antitumor peptides against the cancer cell lines. Elucidating the mechanisms of anticancer properties of the bioactive peptides from camelina will provide confidence to the growers who may seek value-addition. With over 60 peptide based drugs that are globally approved, and an annual sale of US$ 13 billion, design and development of peptides specifically from plant based products remains crucial.

Keywords: Camelina, Peptides, colorectal adenocarcinoma, cytotoxicity
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Citation: . 2016. In vitro Characterization of Camelina Sativa Antitumor Peptides against colorectal Adenocarcinoma Cells. CSBE/SCGAB 2016 Annual Conference, Halifax, 3-6 July 2016.
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Pages -
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Date: juil-16
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Conference name: CSBE/SCGAB 2016 Annual Conference, Halifax, 3-6 July 2016.
Session name: Poster Session (Regular)

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Type: Text.Article
Format: PDF
Publication type: Conference Proceeding
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Coverage: Canada
Language 1: en
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Rights: Canadian Society for Bioengineering
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